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About Blood
History of Blood Transfusion
In 1665 Dr. Richard Lower successfully transfused blood from one dog to another
Jean Denys, physician to Louis XIV of France transfused blood of a lamb into a human in 1667
The first human to human transfusion took place in London in 1818
In 1900 dr. Karl Landsteiner discovered that there were three main human blood groups which became known as A, B and O
The St. John ambulance Brigade in Ireland set up an 'on call' blood donor panel to serve hospitals in the Dublin area
In 1936 the first 'Blood bank' was opened in Cook County Hospital, Chigago - home of the Drama series 'ER'
Before World War II, when a patient required a transfusion, donors had to go to the hospital where the patient was so that they could be directly transfused. These donors were known as 'donors on the hoof'
In 1948 the Minister for Health established the National Blood Transfusion Association in Ireland
The Blood Transfusion Service Board came into existence in 1965

The Origins of Blood
Blood is produced in the bone marrow, a jellylike substance inside the bones. In adults, the spine, ribs, and pelvis are the primary bones that make blood.

As the blood cells develop from the stem cells in the marrow, they seep into the blood that passes through the bones and on into the bloodstream.


The different blood cells have different life spans — red blood cells last about 120 days in the bloodstream; platelets about 10 days; and the various kinds of white blood cells can last from days to years.

The body has feedback systems that tell it when to make new blood cells. For example, if bodily oxygen levels are low, the kidneys produce a hormone called erythropoietin, which stimulates the stem cells in the marrow to produce more red blood cells.

How Blood Travels
Blood moves in two large, continuous circles through a network of blood vessels. The 'right circuit' moves blood from the right side of the heart through the lungs back to the heart (left side). The 'left circuit' moves blood from the heart to the rest of the body and then back to the heart. There are different types of blood vessels: arteries, capillaries, and veins.

Arteries carry blood away from the heart. They branch out into smaller arteries, which connect to capillaries. The capillaries are very narrow — only one cell wide. Inside the capillaries, the red blood cells release oxygen, which passes through the thin capillary walls and into the surrounding tissue. The tissue releases waste products, like carbon dioxide, which passes through the thin capillary walls into the blood.

Blood returns to the heart in the veins. Veins contain one-way valves to keep low-pressure blood flowing towards the heart, even against the pull of gravity. Because the blood in veins contains so little oxygen, it appears bluish in comparison to the bright red of oxygenated blood.
Everybody has Blood - Everybody needs Blood
This red liquid carries oxygen and nutrients to all parts of the body, and carries carbon dioxide and other waste products back to the lungs, kidneys and liver for disposal. It fights against infection and helps heal wounds, so we can stay healthy.

There's no substitute for blood. If people lose blood from surgery or injury or if their bodies can't produce enough, there is only one place to turn -- volunteer blood donors.
Blood Types
Although blood is made of the same basic elements, not all blood is alike. In fact, there are 8 common red blood cell types, which are determined by the presence or absence of certain antigens. Since some antigens can trigger a patient's immune system to attack the transfused blood cells, safe therapy with blood depends on careful blood typing and cross-matching.
Human blood travels 60,000 miles per day on its journey through the arteries, arterioles and capillaries and back through the venules and veins.

The most common blood group is O, accounting for about 46% of the world's population. However, in some areas other blood groups predominate, in Norway for example, type A is the most prevalent.
7% of a person's body weight is made up of blood
The minimum age for donating blood is eighteen
The maximum age for donating blood is 65 (or 60 if you are a first time donor)
The most common blood group is O positive
Rehydrate by drinking plenty of fluids over the next 24-48 hours
The rarest blood group in India O- negative
One in four people will need a blood transfusion at some point in their lives
Only 5% of the population are regular blood donors
A unit of blood lasts for just 35 days.
An average adult has between 5.6 Lts and 6.8 Lts of blood
Blood carries oxygen and nutrients to all parts of the body
Blood carries carbon dioxide and other waste products back to the lungs, kidneys and liver for disposal
There are about 1 billion red cells in two to three drops of blood
 
One car accident victim may require up to 30 units of blood, a bleeding ulcer could require anything between 3-30 units of blood and a coronary artery bypass may use between 1-5 units of blood.

91-40- 2330 2404
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